Endocrine Abstracts

Introduction: The aetiology of obesity-related nephropathy (ORN) is uncertain but may involve hyperfiltration and systemic inflammation.Aims: To define ORN using novel urinary biomarkers that can identify damage to specific regions of the nephron.Methods: Clinical data, blood and urine samples were collected from a consecutive series of 22 patients attending a weight-management clinic (excluding those with diabetes), and from a con...

Introduction: Hypothyroidism presentation can be variable. Some patients are asymptomatic whilst other present with general lethargy and cold intolerance. Depending on the degree of hormone deficiency, patient can also present with by skeletal muscle involvement characterized by muscle aches and weakness (proximal myopathy). In some cases, patients with hypothyroidism will have elevated CK but this usually less that 5000Cases: 1. 46 years old was referre...